Why DNA Evidence Is Not Always Reliable and How Testing Errors Create Reasonable Doubt

On Behalf of Patrick M. Farrell Co L.P.A.
November 17, 2025
Criminal Defense

DNA evidence is often portrayed as infallible, a scientific guarantee of guilt or innocence. But in real criminal cases across Ohio, DNA results are not nearly as perfect as jurors are led to believe. From contamination in crime labs to improper collection techniques at the scene, testing flaws can compromise the most critical parts of an investigation. Our Cleveland criminal defense lawyers at Patrick M. Farrell Co. L.P.A. represent clients throughout Cuyahoga County and Northeast Ohio who are accused of serious offenses involving DNA evidence, and we challenge these results with precision and scrutiny. When a person’s freedom is on the line, DNA must be examined with more than blind trust.

DNA can be compelling, but it is not absolute. Ohio courts and scientific research repeatedly show that improper handling, flawed assumptions, or statistical misinterpretations can turn DNA evidence into misleading conclusions. Understanding these weaknesses is essential for building a strong defense strategy.

How DNA Evidence Is Collected and Used in Ohio Criminal Cases

DNA can come from blood, skin cells, saliva, hair, or bodily fluids. In Ohio, law enforcement uses DNA to:

  • Link a suspect to a crime scene
  • Establish physical contact between individuals
  • Compare samples from CODIS databases
  • Confirm or dispute identity

But the power of DNA depends entirely on the reliability of its collection and processing. Even minor contamination can corrupt results. When cases reach the Cleveland Municipal Court or Cuyahoga County Common Pleas Court, prosecutors often present DNA as definitive. The legal team at Patrick M. Farrell Co. L.P.A. ensures that juries hear the full story, including where the science falls short.

Common Errors That Make DNA Evidence Unreliable

DNA testing has weaknesses like any scientific process. Those weaknesses often create reasonable doubt, especially when investigators mishandle evidence.

1. Contamination at the Crime Scene

Crime scenes are chaotic. Officers, EMTs, and investigators often move through the same space, sometimes without proper protective gear. DNA can be transferred from:

  • Gloves
  • Equipment
  • Clothing
  • Vehicles
  • Prior crime scenes

This contamination can make DNA appear where it never existed.

2. The Risks of Secondary DNA Transfer

Ohio investigators increasingly recognize the danger of DNA transfer through objects or surfaces. A person can unknowingly leave DNA on an item they never touched because:

  • Someone else transferred their DNA
  • The DNA was moved through clothing or fabric
  • Police collected samples improperly

Key takeaway: Finding DNA on an object does not prove the person handled it.

3. Lab Mistakes and Human Error

Crime labs process thousands of samples each year, and mistakes happen. Common errors include:

  • Sample mix ups
  • Incomplete cleaning of equipment
  • Improper storage conditions
  • Mislabeling
  • Data entry mistakes

These errors create misleading or unusable results, yet prosecutors may still present them as reliable science.

4. Problems With Mixed DNA Samples

Many cases involve samples containing DNA from multiple people. Mixed samples are notoriously difficult to interpret and require subjective judgment by analysts. Two different experts may reach completely different conclusions from the same sample.

This uncertainty opens the door to reasonable doubt.

5. Statistical Misinterpretation

DNA results often rely on probability statistics. Prosecutors sometimes exaggerate these numbers to imply certainty that simply does not exist. For example, a statistical match does not mean that only one person could have left the DNA.

When presented incorrectly, these statistics can confuse jurors and distort the truth.

How Investigators Use DNA to Build Criminal Cases

Investigators often rely on DNA early in a criminal investigation to support:

  • Arrest warrants
  • Search warrants
  • Indictments
  • Plea negotiations

But DNA rarely tells the full story. It cannot reveal:

  • When the DNA was deposited
  • How it got there
  • Whether contact was intentional
  • Whether secondary transfer occurred

The legal team at Patrick M. Farrell Co. L.P.A. reviews the state’s forensic work during discovery and challenges assumptions that lack scientific support.

How Our Firm Challenges DNA Evidence in Ohio Criminal Courts

Our Cleveland criminal defense lawyers examine every step of the DNA collection process. Common defense strategies include:

1. Challenging the Chain of Custody

Ohio law requires strict documentation from the moment DNA is collected. Any missing link or unexplained transfer can render the results unreliable.

2. Filing Motions to Suppress Improperly Collected Evidence

If investigators violated Fourth Amendment protections or mishandled evidence, we may move to suppress that DNA entirely.

3. Retaining Independent DNA Experts

Independent analysis often reveals contamination, misinterpretation, or lack of scientific certainty. These experts provide testimony prosecutors cannot ignore.

4. Highlighting Mixed or Low Quality Samples

Weak, degraded, or mixed samples create significant doubt and often cannot support a conviction.

5. Exposing Statistical Misrepresentations

Our attorneys ensure juries understand the limits of probability statistics so that numbers are not used to exaggerate the truth.

If you're looking for a Cleveland criminal defense lawyer near me who understands DNA evidence defense, working with an experienced legal team early can prevent small testing errors from turning into major legal consequences.

Why DNA Evidence Does Not Always Mean Guilt

Even when DNA is found at a scene, it may have arrived there through innocent or unrelated circumstances. DNA cannot prove someone committed a crime, only that genetic material is present. When the evidence is weak, contaminated, or scientifically questionable, juries must hear why it cannot support guilt beyond a reasonable doubt.

DNA Testing Errors Can Change the Outcome of a Case

DNA may be powerful, but it is not foolproof. Crime scenes are unpredictable environments, labs make mistakes, and mixed DNA samples can be nearly impossible to interpret with certainty. When prosecutors rely on DNA as their strongest evidence, a thorough and strategic defense becomes essential to uncover scientific weaknesses and protect your future. The legal team at Patrick M. Farrell Co. L.P.A. represents clients in Cleveland, Lakewood, and throughout Northeast Ohio with a commitment to challenging unreliable forensic evidence and exposing errors that create reasonable doubt. Your case deserves a defense grounded in science, accuracy, and unwavering advocacy.

If you’ve been arrested in Cleveland, Lakewood, or anywhere in Northeast Ohio, don’t wait. Call Patrick M. Farrell Co. L.P.A. at (216) 661-5050 or request a free consultation now. When DNA evidence threatens your future, a strategic defense can make all the difference.

Text or Call: (216) 661-5050 • Contact: Submit a Request • Email: cindy@patfarrelllaw.com

Why Choose Patrick M. Farrell Co. L.P.A.?

At Patrick M. Farrell Co. L.P.A., we prioritize your rights and freedom. Our experienced team is dedicated to providing you with personalized defense strategies that yield results.